3rd Generation of Tissue Repair

Zantop T, Petersen, W.
"Arthroscopic Implantation of a matrix to cover large chondral defect during microfracture: case report with video illustration. "
Arthroscopy. 2009 Nov;25:1354-1360.

Erggelet C, Endres M, Neumann K, Morawietz L, Ringe J, Haberstroh K, Sittinger M, Kaps C.
"Formation of Cartilage Repair Tissue in Articular Cartilage Defects Pretreated with Microfracture and Covered with Cell-Free Polymer-Based Implants."
J Orthop Res. 2009 Oct;27(10):1353-60.

Kreuz PC, Muller S, Ossendorf C, Kaps C, Erggelet C.
"Treatment of focal degenerative cartilage defects with polymer-based autologous chondrocyte grafts: four year clinical results."
Arthritis Res Ther. 2009 Mar 5;11(2):R33

Ossendorf C, Kaps C, Kreuz PC, Burmester GR, Sittinger M, Erggelet C.
"Treatment of posttraumatic and focal osteoarthritic cartilage defects of the knee with autologous polymer-based three-dimensional chondrocyte grafts: 2-year clinical results."
Arthritis Res Ther. 2007;9(2):R41.

Schmelzeisen R, Schimming R, Sittinger M.
"Making bone: implant insertion into tissue-engineered bone for maxillary sinus floor augmentation-a preliminary report."
Journal of Craniomaxillofacial Surgery. 2003 Feb;31(1):34-9.


Stem and Precursor Cells

Kalwitz G, Endres M, Neumann K, Skriner K, Ringe J, Sezer O, Sittinger M, Häupl T, Kaps C.
"Gene expression profile of adult human bone marrow-derived mesenchymal stem cells stimulated by the chemokine CXCL7. "
Int J Biochem Cell Biol. 2009 Mar;41(3):649-58.

Neumann K, Dehne T, Endres M, Erggelet C, Kaps C, Ringe J, Sittinger M.
"Chondrogenic differentiation capacity of human mesenchymal progenitor cells derived from subchondral cortico-spongious bone."
J Orthop Res. 2008 Nov;26(11):1449-56.

Endres M, Neumann K, Häupl T, Erggelet C, Ringe J, Sittinger M, Kaps C.
"Synovial fluid recruits human mesenchymal progenitors from subchondral spongious bone marrow."
J Orthop Res. 2007 Oct;25(10):1299-307.

Hegewald AA, Ringe J, Bartel J, Krüger I, Notter M, Barnewitz D, Kaps C, Sittinger M.
"Hyaluronic acid and autologous synovial fluid induce chondrogenic differentiation of equine mesenchymal stem cells: a preliminary study."
Tissue Cell. 2004 Dec;36(6):431-8.

Ringe J, Kaps C, Burmester GR, Sittinger M.
"Stem cells for regenerative medicine: advances in the engineering of tissues and organs."
Naturwissenschaften. 2002 Aug;89(8):338-51.


Drug Screening

Smolian H, Thiele S, Kolkenbrock H, Zacher J, Aicher W, Schultz O, Burmester GR, Sittinger M.
"Establishment of an in vitro model for rheumatoid arthritis as test system for therapeutical substances."
ALTEX – Alternativen zum Tierexperiment. 2001;18(4):265-80.

Andreas K, Häupl T, Lübke C, Ringe J, Morawietz L, Wachtel A, Sittinger M, Kaps C.
"Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. "
Arthritis Res Ther. 2009;11(1):R15. Epub 2009 Feb 3.

Andreas K, Lübke C, Häupl T, Dehne T, Morawietz L, Ringe J, Kaps C, Sittinger M.
"Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study. "
Arthritis Res Ther. 2008;10(1):R9. Epub 2008 Jan 18.

Häupl T, Yahyawi M, Lübke C, Ringe J, Rohrlach T, Burmester GR, Sittinger M, Kaps C.
"Gene expression profiling of rheumatoid arthritis synovial cells treated with antirheumatic drugs. "
J Biomol Screen. 2007 Apr;12(3):328-40.